Lesson 1  - Blood Clotting

Lesson Objectives

A. Content Objective: The skin and mucous membranes form primary defense again pathogens and blood clotting helps maintain this barrier by fixing cuts using a complex series of chemical reactions.

B. Language Objective: The cascade reaction, clotting factors, fibrinogen and fibrin all work together to form a blood clot.

C. Syllabus Details:

Clotting

i. The skin and mucous membranes form a primary defense against pathogens that cause infectious disease

ii. Cuts in the skin are sealed by blood clotting

iii. Clotting factors are released from platelets

iv. The cascade results in the rapid conversion of fibrinogen to fibrin by thrombrin

Resources

Clotting

Video:

Innate Immunity - Watch until 3:00 (i)

Immune System Primary defences  (i)

Blood Clotting (ii-iv)

Reading:

Bioninjia - Blood Clotting (ii-iv)

Bioninjia - Surface barriers 

Blood clotting 

Immunity (i-iv) - focus on 1,9 and 10

Book:

Oxford pg. 305, 465-470

Activites

Activity 1  

Immune System - The Amoeba Sisters

Focus on the big picture and create a set of notes outlining the three lines of defence

Activity 2 

Blood Clotting Skits

Objective - Create a skit that shows blood clotting using all the keywords below.

Guidelines:

• You must use at least 5 different props in the skit...you can work with in groups of up to 4 people.

• You need a narrator and the following keywords must be used.

• You will then film the skit and put it in this folder. 

• We will watch them all and hopefully laugh!

Keywords:

Blood vessels
Platelets

Fibrin strands

Coagulation Cascade

Vasoconstriction

prothrombin (enzyme)

thrombin (enzyme)

fibrinogen

fibrin

Home Learning

A. Strengthen Your Skills

 Mr.C's Notes 

 B.  Expand Your Knowledge

Here is the full description of blood clotting - Good for medical school

Muscosal Immunity Overview - Interesting, but I'm a biology teacher