Lesson 1 - Blood Clotting
Lesson Objectives
A. Content Objective: The skin and mucous membranes form primary defense again pathogens and blood clotting helps maintain this barrier by fixing cuts using a complex series of chemical reactions.
B. Language Objective: The cascade reaction, clotting factors, fibrinogen and fibrin all work together to form a blood clot.
C. Syllabus Details:
Clotting
i. The skin and mucous membranes form a primary defense against pathogens that cause infectious disease
ii. Cuts in the skin are sealed by blood clotting
iii. Clotting factors are released from platelets
iv. The cascade results in the rapid conversion of fibrinogen to fibrin by thrombrin
Resources
Clotting
Video:
Innate Immunity - Watch until 3:00 (i)
Immune System Primary defences (i)
Reading:
Bioninjia - Blood Clotting (ii-iv)
Immunity (i-iv) - focus on 1,9 and 10
Book:
Oxford pg. 305, 465-470
Activites
Activity 1
Immune System - The Amoeba Sisters
Focus on the big picture and create a set of notes outlining the three lines of defence
Activity 2
Blood Clotting Skits
Objective - Create a skit that shows blood clotting using all the keywords below.
Guidelines:
You must use at least 5 different props in the skit...you can work with in groups of up to 4 people.
You need a narrator and the following keywords must be used.
You will then film the skit and put it in this folder.
We will watch them all and hopefully laugh!
Keywords:
Blood vessels
Platelets
Fibrin strands
Coagulation Cascade
Vasoconstriction
prothrombin (enzyme)
thrombin (enzyme)
fibrinogen
fibrin
Home Learning
A. Strengthen Your Skills
B. Expand Your Knowledge
Here is the full description of blood clotting - Good for medical school
Muscosal Immunity Overview - Interesting, but I'm a biology teacher