Content Objective: XXX
Language Objective: XXX
Syllabus Details:
C1.1.11 (HL)—Intracellular and extracellular enzyme-catalysed reactions
C1.1.12 (HL) —Generation of heat energy by the reactions of metabolism - "Include the idea that heat generation is inevitable because metabolic reactions are not 100% efficient in energy transfer. Mammals, birds and some other animals depend on this heat production for maintenance of constant body temperature."
C1.1.13 (HL)—Cyclical and linear pathways in metabolism - "Use glycolysis, the Krebs cycle and the Calvin cycle as examples."
C1.1.14 (HL)—Allosteric sites and non-competitive inhibition -"Students should appreciate that only specific substances can bind to an allosteric site. Binding causes interactions within an enzyme that lead to conformational changes, which alter the active site enough to prevent catalysis. Binding is reversible. "
C1.1.15 (HL)—Competitive inhibition as a consequence of an inhibitor binding reversibly to an active site - "Use statins as an example of competitive inhibitors. Include the difference between competitive and noncompetitive inhibition in the interactions between substrate and inhibitor and therefore in the effect of substrate concentration."
C1.1.16 (HL) —Regulation of metabolic pathways by feedback inhibition - "Use the pathway that produces isoleucine as an example of an end product acting as an inhibitor."
Activity 2
Activity 3
A. Strengthen Your Skills
B. Expand Your Knowledge