Content and Language Objective: Describe the transmission and effect of HIV on the body and provide an example of a zoonotic and non-zoonotic disease, and explain how antibiotics work and why they do not work against viruses.
Book Reference: 288-289, 457-458
Homework: See HW Page
Syllabus Details:
White blood cells release histamine in response to allergens
Histamines cause allergic symptoms
Pathogens can be species specific although others can cross species barriers
Effects of HIV on the immune system and methods of transmission
Antibiotic blocks processes that occur in prokaryotic cells but not in eukaryotic cells
Viruses lack a metabolism and cannot therefore be treated with antibiotics.
Florey and Chain’s experiments to test penicillin on bacterial infections in mice
Activity 1 - Histamine and Allergies
Please watch the video below, how do allergies form, and collect the following information:
The role of APC in allergies, the role of mast cells, and histamine. --
*Keep it general - you don't need to discuss every step
Watch this video about histamine:
Where is histamine released?
What does it do?
Answer the following question
Summarize how allergies form (using vocab such as antigens, allergen, phagocytes, APC, helper T cells, B Cells, antibodies, mast cells, histamines).
Activity 2 - HIV and AIDS
Watch this video - “HIV and AIDS”
Followup Questions:
-What does HIV do to the immune system?
-What are the most common ways to become infected with HIV?
Activity 3 - Antibiotic Use
Readings
Chemical & Engineering - Penicillin - Focus on the mice studies carried about by Florey and Chain and their work on humans after that.
Videos
Explain how antibiotics work in prokaryotic cells and why they are useless against viruses and eukaryotic cells using one of the following methods. You may work with someone else.
an obituary
a Nightmare
a recipe
a witness statement
Activity 4 - Pathogens - Zoonotic and Non-zoonotic
Please complete this data analysis question set.
Activity 5 - Monoclonal Antibodies
A. Strengthen Your Skills
Mr. C's Notes on Allergies, HIV, Antibiotics
To help you sleep at night - 10 Deadly Diseases That Hopped Across Species
CDC - Zoonotic Diseases
B. Expand Your Knowledge
Specific mechanisms for penicillin resistance
Got Allergies - Thank Evolution
Allergens Evolved to Save our Lives?