A. Content Objective: The four types of macromolecules each have their own unique structure and function in living things and are composed of carbon.
B. Language Objective: Create a roundhouse diagram that shows the structure, functions, types of macromolecules. Use the syllabus details to guide you. Instructions for how to do a roundhouse diagram.
C. Syllabus Details:
i. Molecular biology explains living processes in terms of the chemical substances involved
ii. Carbon atoms can form four covalent bonds allowing a diversity of stable compounds to exist
iii. Life is based on carbon compounds including carbohydrates, lipids proteins and nucleic acids
iv. Metabolism is the web of all the enzyme-catalyzed reactions in a cell or organism
v. Anabolism is the synthesis of complex molecules from simpler molecules including the formation of macromolecules from monomers by condensation reactions
vi. Catabolism is the breakdown of complex molecules into simpler molecules including the hydrolysis of macromolecules into monomers
vii. Urea as an example of a compound that is produced by living organisms but can also be artificially synthesized
viii. Monosaccharide monomers are linked together by condensation reactions to form disaccharides and polysaccharide polymers
ix. Drawing molecular diagrams of alpha-D-glucose, beta-D-glucose, D-ribose, a saturated fatty acid and a generalized amino acid
x. Identification of biochemical such as sugars, lipids, or amino acids from molecular drawings
xi. Structure and function of cellulose and starch in plants and glycogen in humans
Activity 1 - Pre-Lesson Work:
Expectations: Create a set of notes, using the roundhouse diagram, of the syllabus statements above. The Roundhouse diagram needs to be handmade on a piece of paper or iPad.
Links:
Roundhouse Instructions - Read this first
Roundhouse Blank Sheet - import into your iPads or print a copy
Roundhouse Example - It's not a great example.
Video:
Amoeba Sisters - Biomolecules (start at 6:30) - iii, ii, x
Why Carbon is a Tramp - 2min - 5 min - i, ii, iii
Generalized Structures of Macromolecules - ix, x
Identifying Macromolecules - x
Structure and function of cellulose and starch - x
Readings:
Bioninja - Molecular Biology - i
Bioninja - Organic Compounds - ii, iii, ix, x, viii
Bioninja - Polymers and Monomers - iv, v, vi
Bioninja - Polymers - xi, viii
Fake Pee! Vitalism disproved - vii
Book Resources:
Pearson: 53-59, 67-74
Activity 3 - Making Molecular Models of carbohydrates and amino acids
A. Strengthen Your Skills
Molecules and Metabolism - Excellent resources
Carbohydrates and Lipids- Excellent resources
Macromolecules - Blank Summary Sheet
B. Expand Your Knowledge