Content Objective: To describe how the lock and key model and the induced fit model works using the following vocabulary; molecular motion, collision, enzyme, enzyme substrate complex, substrate, products, covalent bonds, active site, immobilized enzymes, activation energy, induced fit, competitive inhibition, non-competitive inhibition .
Language Objective: Create a set of notes that meet the content objective and the syllabus statements below.
Syllabus Details:
Lesson 25 (Activity 1 and Activity 2)
Metabolic pathways consist of chains and cycles of enzyme-catalysed reactions
Enzymes lower the activation energy of the chemical reactions that they catalyse
Enzyme catalysis involves molecular motion and the collision of substrates with the active site
Temperature, pH, and substrate concentration affect the rate of activity of enzymes
Enzymes can be denatured
Enzymes have an active site to which specific substrates bind
Enzyme inhibitors can be competitive or non-competitive.
Lesson 26 (Activity 3)
End-product inhibition of the pathway that converts threonine to isoleucine.
Calculating and plotting rates of reaction from raw experimental results.
Distinguishing different types of inhibition from graphs at specified substrate concentration.
Lesson 27 (Activity 4 and 5)
Immobilized enzymes are widely used in industry
Methods of production of lactose-free milk and its advantages
Activity 3 - Factors affecting Enzyme rates
Activity 4 - Allosteric inhibition
*Allosteric inhibition is an example of non-competitive inhibition
1. Watch this video - listen up to 40 seconds.
2. End product inhibition - an example of allosteric inhibition
3. Mr. C's explanation of isoleucine video
Task: Explain how end product inhibition works using one of the following roles (you can work with a partner). Please upload to Google Classroom:
A love song (1 bonus point on a summative test for singing it)
A opera (1 bonus point on a summative test for singing it)
A blues or rap song (1 bonus point on a summative test for singing it)
Shadow puppet play (2 minute max)
A TV commercial (30 Sec max)
Activity 5 - Immobilized Enzymes
Video: Immobilized Enzymes
Reading: Lactose-Free Milk Production
Video: Lactose-Free Milk Production Question Answer
Task: Using the information above, create a 1 page summary (handwritten preferred) on the use of immobilised enzymes and the production of lactose-free milk
Activity 6 - Practice Problems
A. Strengthen Your Skills
B. Expand Your Knowledge